However, Season 8, Episode 8: “Heart-Shaped Box” upped the ante quite a bit, when Lexie's writer patient — who was clearly a stand-in for Shonda, don't argue — talked about the love triangle between her book's heroine, Kate, good-guy Nathan, and bad-boy Alexander. Lexie clearly found resonance between the story and her real life, and we can't help but think the writer calling Alexander Kate's "soul-mate" was Shonda's way of telling us the same is true of Lexie and Mark.
What do you think? Is Mark really Lexie's soul mate? Or do you think Grey's may eventually go in a different direction? After all, even the writer-patent wasn't positive Kate and Alexander would end up together at the end of her series — maybe that's Shonda's way of telling us nothing is set in stone.