She leaves for love. If Cristina isn't saying see ya to go be great in another job, we hope that she's doing it for another positive reason, such as falling in love with someone who lives elsewhere (assuming that elsewhere has a hospital that will hire her). While Cristina dropping everything for a guy seems out of character, if the writers play it right it could be symbolic of her finally learning to embrace every element of life, not just work. We'd be fine with that — as long as she could continue being a super surgeon at the same time.
A heroic death. Actually, we don't want this one at all, but this is Grey's Anatomy, so we'd be remiss not to ponder the possibility that Shonda Rhimes will use Sandra's departure to stab us brutally in the heart. So, we'll just say this: If the writers insist on killing Cristina (please, oh please, no!), they better at least let her go out in some triumphant, heroic way where she rescues twenty children from a horrible death, or saves the President of the United States or something. But mostly they shouldn't kill her. Yeah, let's go with that.
TVLine has also put forth some ideas on Cristina's swan song: 1. Addison (Kate Walsh) invites Cristina to St. Ambrose Hospital in Los Angeles to open her own cardiothoracic wing. 2. Burke returns to Seattle just long enough to mend ties with Cristina and sweep her away. 3. Cristina returns to the Mayo Clinic. 4. Cristina gives away her own heart to save someone else — another idea for the afore-mentioned heroic death. We like all these ideas from our fellow TV journalists, too!
But how do you want to see Cristina leave? Sound off in the comments below.