Grey's Anatomy

6 TV Couples Who Seemed Meant to Be — But Weren’t

While the fate of Cristina (Sandra Oh) and Owen's (Kevin McKidd) relationship isn't set in stone, the Season 9 finale completed their two season divorce arc with a pretty definitive split, and Sandra Oh's departure from the show at the end of Season 10 seems to put a nail in the coffin of whatever tattered mess of a romance may be left.

Romantic roller coasters are par for the course when you sign on to a Shonda Rhimes show, but until Season 9 ripped out our hopeful Owen/Cristina loving hearts and crushed them, we were convinced these two crazy docs were made for each other. We're still struggling to accept that Shonda had other plans.

This is far from the first time we've been tricked into a sense of shipper calm, convinced certain couples were headed for a Happily Ever After, only to have the rug pulled out from under us by departing characters, unexpected deaths, and plain ol' being wrong.

We've gathered six other ships we were sure were meant to be — and weren't.

Warning: This gallery contains spoilers!