This got us thinking about the original cast members — along with Sandra, they are Patrick Dempsey, Ellen Pompeo, Chandra Wilson, Justin Chambers, and James Pickens Jr. —and how much we'd miss them if they left. Each of the original characters brings a different certain something to the show, and they'd all leaving gaping holes if they chose to leave.
However, not all characters are made equal, and every fan has his or her favorite. So, we want to know: Between Meredith, Derek, Cristina, Bailey, Alex, and Richard, whose departure would break your heart the most?
Can you not imagine Grey's without the titular protagonist and her signature monologues opening each episode? Is the show just too dreary without McDreamy? Is Bailey truly the heart of the hospital for you? Do you need Richard's wisdom, Cristina's snark, or Alex's grumpiness?
We know this is a hard choice, but we want you to weigh in: Which character would you miss the most?
Vote in our poll, and sound off in the comments below!