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Grey's Anatomy Season 10 hasn't even begun airing, but speculation has already started about some of the original cast members — including Patrick Dempsey (Derek Shepherd) and Ellen Pompeo (Meredith Grey) — potentially leaving the show after the season is over and their contracts are up. And speculation as become reality in the case of Sandra Oh, who has confirmed she's leaving when the season is up.

This worry isn't coming out of nowhere. On top of Sandra leaving, at the recent Television Critics Association press tour, the bigwigs at ABC made it clear that they hope that Grey's will last for many years to come — with or without the original cast. On top of that, Shonda Rhimes discussed how she hopes to give any of the originals who choose to leave "the beautiful exit they deserve." 

Along with Sandra, Patrick, and Ellen, the other originals are Chandra Wilson (Miranda Bailey), Justin Chambers (Alex Karev), and James Pickens Jr. (Richard Webber).

We want to know: Will you keep watching the show with Cristina gone? Will more originals leaving make you stop? Does it depend on who else exits for good?

Vote in our reaction buttons, and sound off in the comments below!

Catch the Grey’s Anatomy Season 10 premiere on Thursday, September 26, 2013, at 10 p.m. ET/PT on ABC.


Credit: Celebified Photo: Grey's Anatomy Faces Major Potential Cast Member Exits In Season 10, Including Ellen Pompeo, Patrick Dempsey, Sandra Oh, Justin Chambers, And Chandra Wilson!