Grey’s Anatomy celebrates its milestone 200th episode with Season 10, Episode 4: “Puttin’ on the Ritz,” but we’re already thinking ahead to Episode 5.

In addition to James Remar going from Dexter’s ghost mentor father to Alex Karev’s estranged junkie dad in Episodes 4 and 5 (and beyond), there will be drama for everyone at Grey Sloan Memorial — especially Callie and Owen.

According to the official synopsis — which you can read in full below — there will be an “emotional” situation for them to handle, in addition to the turmoil that Callie is currently going through with her adulterous wife, Arizona.

Things won’t be much better for Meredith, either. She’ll continue her struggles with juggling motherhood and her work, while Stephanie deals with a different mother of a problem: impressing Jackson’s mom.

Read on for the full synopsis, then hit the comments with what you’re most excited to see.

“Meredith jumps back into work but finds it hard to excel at both motherhood and being a surgeon. Stephanie tries to make a good impression on Jackson’s mom, and Jo finds herself overly involved with her new patient. Meanwhile, Callie and Owen deal with an emotional situation regarding a patient.”

The next episode of Grey’s Anatomy airs on Thursday, October 10 at 9 p.m. ET on ABC.
Alyse Whitney is Assistant Editor at Wetpaint Entertainment. Follow her on Twitter and Google+.