Credit: Kelsey McNeal/ABC Photo: Grey's Anatomy Season 10, Episode 10: Jo Wilson and Alex Karev

In the time we’ve known Alex Karev (Justin Chambers) on Grey’s Anatomy, he hasn’t been much of a relationship guy. In the few times we’ve seen him show a real interest in someone, we’ve never seen him let anyone in like he did with Izzie (Katherine Heigl)... until Jo (Camilla Luddington) arrived on the scene, that is.

But Camilla wants you to know that Jo is no Izzie 2.0 — this intern is a whole ‘nother animal, especially where her relationship with Alex is concerned. And while she can understand that the fact that Jo and Izzie came from similar backgrounds might make Jo seem like a new and improved version of Alex’s ex-wife, Camilla insists that’s not the case.

Why not? First of all, their ideas of interior decorating couldn’t be more different. “I feel like Izzie would’ve made it look all pretty,” Camilla told TV Line of Alex’s pathetic living space. “It’s still a little bit trashy, and I can see Jo and Alex thinking that it looks nice. Like that’s nice for them.”

True — if Izzie lived there, not only would it look like it was decorated by Anthropologie, but there would be muffins. All. The. Time.

“I feel like Alex can be more himself in front of Jo,” Camilla said. “She doesn’t see anything wrong with him. His hotheadedness is the same as hers. She accepts them. I almost see them as partners in crime.

And in the case that Izzie might show back up in the future, Camilla’s not concerned for Jo. To her, there’s no question that she’d fight.

“I think Jo would want to throw down,” Camilla laughed. “I really do. That would be very interesting. I don’t know what Alex would do. I would like to think he would stay with Jo.”

Who would win in a fight — Izzie or Jo? Place your bets below!

Source: TV Line