Credit: IMDb Photo: Katherine Heigl and James Remar

Katherine Heigl has a lot to talk about with James Remar, a co-star of hers in her new NBC drama pilot, State of Affairs — namely, the fact that they are TV family already via Grey's Anatomy.

That's because James played Izzie's former father-in-law, Jimmy Evans — the estranged father of Alex (Justin Chambers), Izzie's ex-husband.

And now, as writer-director Joe Carnahan revealed on Twitter, James is on the set of Katherine's new project. (In case that name rings a bell, Joe also wrote and directed The A-TeamThe Grey, and the pilot of The Blacklist.)

In the spy-centric drama — which Joe co-wrote with The Following's Alexi Hawley — Katherine plays Charleston "Charlie" Whitney Tucker, who briefs the President (played by Alfre Woodard) on international crises. She's also the ex of President's deceased son. The show described as a mix of Scandal and The West Wing.

Funnily enough, this isn't the first time Katherine and James have shared the screen. They also co-starred in a 2002 episode of The Twilight Zone, in which Katherine played a woman who time-travels to 1880s-era Austria to kill baby Adolf Hitler, with James playing the future Nazi leader's father.

So now we're imagining their conversation on the New York City set of State of Affairs to go like this: "Oh, hey, James. Good to see you. Too bad Alex never reconnected with his pops while I was on Grey's, huh? Hey, remember that time I killed your Nazi baby?"

Dan Clarendon is an assistant editor at Wetpaint Entertainment. Follow him on Twitter and Google+!