Credit: Ellen Pompeo on Instagram Photo: Ellen Pompeo and Sandra Oh

Season 10 of Grey's Anatomy is nearly a wrap — and with it wraps Sandra Oh's work as Cristina Yang.

Sandra's on-screen "person," Ellen Pompeo (Meredith Grey), pays tribute to her departing colleague and bestie with this Instagram selfie, presumably taken on their last day of working together.

"So proud of the work we've done together, @iamsandraoh," Ellen writes. "We've laughed, we cried, we've kicked some serious acting ass together. #SOGRATEFUL

It's not the first time Ellen has praised the lovely Ms. Oh. In 2012, she told E! Online, "I do love acting with Sandra Oh. That's my favorite part of the show, I'd have to say. Well, I love Patrick [Dempsey], too, but me and Sandra have something special.

And in September, Ellen continued the lovefest on Watch What Happens Live!:

"I think that Sandra is gonna deliver her best performances of the whole entire series this year because it's her exit. She's gonna bring it, and it's gonna be some of the best entertainment you'll ever see for sure. Sandra cares deeply about what she does, and she's definitely gonna entertain the ass off y'all."

We'll miss seeing these two bond together on our TV screens every week, but we hope Sandra continues guest-starring in Ellen's Instagram feed!

Sources: E! Online, Watch What Happens Live!

Dan Clarendon is an assistant editor at Wetpaint Entertainment. Follow him on Twitter and Google+!