On Grey's Anatomy Season 10, Episode 21: "Change of Heart," Cristina (Sandra Oh) has to deal with losing out on the Harper Avery, Alex (Justin Chambers) grapples with his big decision, and a familiar face returns to town.

What else can you expect as the season heads into the home stretch? We've gathered all of the biggest hints, sneak peeks, and spoilers about the episode right here so you can get a taste of what will go down when we return to Grey Sloan memorial tomorrow.
 

The Official Synopsis

Let's start with the official synopsis of the episode:

Jackson [Jesse Williams] is given the daunting task of delivering disappointing news to the doctors. Meanwhile, Derek's [Patrick Dempsey] sister Amelia [Caterina Scorsone] drops by for a surprise visit, Richard [James Pickens Jr.] surprises Catherine [Debbie Allen] in Boston, and when Bailey [Chandra Wilson] gets frustrated by the slow pace of her research, she makes a risky decision.


We can't be the only ones who're excited to have Amelia back in town, but it looks like Meredith and Derek are less than thrilled to see her pop up unannounced. Hasn't she ever heard of calling ahead?
 

Anger at the Averys

The synopsis also has a lot of emphasis on the Averys, with Jackson having to deliver bad news, and Richard visiting Catherine. Are either or both of these things linked to Cristina losing the Harper Avery award? Maybe Jackson is the one who's tasked with letting the other docs know Cristina lost. And would Richard use his romantic connection to try to learn why Cristina didn't win?

Either way, we know that Meredith, at least, is not pleased with anyone linked to the Avery fam, as we see in this sneak peek.


Poor April! We're sure Meredith will apologize later, but for now April is caught in the crossfires. That wouldn't be fun under any circumstance, but it must really sting right now, since she and Jackson aren't exactly seeing eye-to-eye.

Alex's Big Choice

Meanwhile, in this sneak peek Alex snaps at Arizona when it looks like she's trying to convince him not to take the private practice job.


It sounds like he's leaning towards taking the gig. Could he really be leaving Grey Sloan Memorial?
 
 

Bailey's Risky Decision

This synopsis teases that Bailey makes a risky decision. Will it pay off, or backfire? In Episode 22, Stephanie realizes some kind of truth about the case, which is worrying, and there's even some speculation that Bailey could find herself in legal trouble over this case. We hope we're interpreting the clues wrong, though. We'd love it if Bailey's risk pays off in a big win instead of a big disaster.

Are you looking forward to this episode? Let us know in the comments below!

Catch this episode tomorrow, Thursday, April 24  at 9 p.m. ET on ABC.

Rebecca Martin is an Associate Editor at Wetpaint Entertainment and our resident Game of Thrones, Breaking Bad, and genre TV expert. Follow her on Twitter and Google+!