Credit: Bob D'Amico/ABC © 2014 American Broadcasting Companies, Inc. Photo: Jo Wilson (Camilla Luddington)

Alex's (Justin Chambers) abrupt departure from Grey Sloan Memorial is changing the dynamic of the whole hospital on Grey's Anatomy. But no one is affected more than his girlfriend, Jo (Camilla Luddington), as Camilla explains on Home & Life.

During the Brit actress's April 30 appearance on the daytime talk show, she brought along a sneak peek from the episode airing tonight, May 1 — Season 10, Episode 22: "We Are Never Getting Back Together."

Click here to see the sneak peek.

As the scene begins, Alex is dropping Jo off at the hospital — late.

"This has got to stop," she says. "We can't stay up until three in the morning talking about how much you love your new job."

"Well, that's not all we were doing," replies Justin smugly.

She tells him she misses him at the hospital, and he tells her she can always call him for help. She riles at the implication that she can't do her job without him.

"I am perfectly capable of making medical decisions without the help of my boyfriend."

"Dude, you're being weird. Get out of the car before you escalate."

"Jo really misses him," Camilla tells the hosts after the clip plays. "She doesn't want to have to rely on him, but she ends up panicking that entire episode and trying to get him on the phone. She really wants him there."

How will the hospital cope without Alex? Speculate away in the comments section below.

Grey's Anatomy Season 10, Episode 22 — "We Are Never Getting Back Together" — airs tonight, Thursday, May 1, at 9 p.m. ET on ABC.

Source: Home & Family

Dan Clarendon is an assistant editor at Wetpaint Entertainment. Follow him on Twitter and Google+!