Meredith and Derek (Patrick Dempsey) in the Season 2 Finale:
After a year of longing glances, occasional makeouts and one too many heartbreaking speeches, Meredith and Derek finally gave in to temptation at Seattle Grace’s prom night. The way we see it, Mer didn’t have a choice. Did you see the way he was looking at her from across the dance floor? We mean, really.