John Stamos: Jesse Katsopolis
John Stamos is arguably the hunkiest male actor on Full House, and he had no problem staying in Hollywood after the show went off the air. Not only did this Greek actor land a starring role on ER from 2006 to 2009 as Dr. Tony Gates, but he later took his talent to the stage to play Albert in the Broadway revival of Bye Bye Birdie. Being super musical himself (who remembers his performances with the Beach Boys on Full House?), the dark-haired actor also played Dr. Carl Howell on multiple episodes of Glee in 2010.
John found love with model Rebecca Romijn in 1994, and the two got married in 1998. Sadly (for them, not Stamos-lovin' ladies everywhere), the couple divorced in 2005.