Rachel McAdams as Regina George
Rachel McAdams is essentially the opposite of Lindsay Lohan. Just after Mean Girls, she and Ryan Gosling starred in another quotable film: The Notebook. She continued with a mix of comedy and drama, including Wedding Crashers, The Time Traveler’s Wife, Sherlock Holmes, Midnight in Paris, and The Vow — just to name a few!
Next up, she’s starring in Passion, a dark, seductive Black Swan-esque thriller, with Prometheus’ Noomi Rapace.