Most Memorable TV Weddings Countdown!

When Izzie (Katherine Heigl) took the reigns on planning Meredith (Ellen Pompeo) and Derek’s (Patrick Dempsey) nuptials, they couldn’t say no to anything. (Brain tumor = ultimate trump card.) She became a complete bridezilla, turning it into her dream wedding. Luckily, Alex (Justin Chambers) was a willing groom, so a list-minute switcheroo made it hers after all. While they enjoyed the pomp and circumstance, Meredith and Derek swapped vows on a Post-it note. Everyone got what they wanted... temporarily. At least we have the memories!