The rapper's fiancée, Liz Trujillo, was rushed to the hospital after an overdose on painkillers, according to TMZ.
Flav and Liz, who is 39, have been filming the new season of VH1's Couples Therapy in order to work out their issues together.
The couple have a child together.
Liz was taken to the hospital in an ambulance, and sources say she'll be released soon.
Flavor Flav — who has starred on Flavor of Love — was arrested last year following a domestic dispute with Liz last fall in which Flav reportedly flipped out after she accused him of cheating.
We're wishing Liz a speedy recovery.
Source: TMZ, TMZ