Jennifer Aniston and Brad Pitt at the Premiere of Along Came Polly on January 12, 2004
It was Hollywood's dream come true: silver-screen heartthrob marries queen of the small screen. Jennifer Aniston and Brad Pitt got hitched in 2000 in a lavish Malibu affair complete with fireworks and endless Dom Perignon. Five years later, Brad allegedly fell for his Mr. and Mrs. Smith co-star Angelina Jolie during filming. Jennifer filed for divorce in March 2005, and by January 2006, Angelina was pregnant with Brad's first child. Three kids later, Brangelina is set to make it official.