Lizzy Caplan as Janis Ian
In addition to being virtually unrecognizable now, Lizzy has had quite the career post-Mean Girls. Though she was in a few big films (Cloverfield, 127 Hours, Hot Tub Time Machine), she is mostly known for her TV work on the cult hit Party Down, HBO’s True Blood, and the breakout comedy New Girl.
In 2012, she stole the show in Bachelorette — alongside Kirsten Dunst, Rebel Wilson, Isla Fisher, and Party Down co-star Adam Scott — plus 3, 2, 1... Frankie Go Boom with Sons of Anarchy star Charlie Hunnam and Save the Date with Community’s Alison Brie. She also co-starred in Marvel One-Shot Item 47, an Avengers Blu-ray extra, with Jesse Bradford and currently wows as Virginia Johnson on Showtime’s Masters of Sex.