The last time we saw our favorite vamps, everyone was heading in different directions post-graduation. Matt took Rebekah up on her offer to travel the world, Damon and Elena finally made things official, Caroline got the A-OK to bring Tyler back to Mystic Falls, and Stefan, well, poor Stefan found himself locked in a box at the bottom of a quarry thanks to Silas. So where does that leave the Scooby Gang come fall?

The Vampire Diaries returns October 3 with Season 5, Episode 1 (“I Know What You Did Last Summer”), and it sounds like things start off with a bang — literally, for Matt and Rebekah. TVD fans, here’s what you can expect from the Season 5 opener (warning: major spoilers ahead!).

Elena and Caroline are Whitmore College-bound! You’d think that if you had the ability to live forever, you’d postpone your college plans for another year or so, but not Elena and Caroline. These two BFFs are headed to Whitmore College for their freshman year, but it unfortunately won’t be all sorority parties, football games, and all-nighters for Elena and Caroline. Just when they think they’ve escaped Mystic Falls and its abundance of supernatural activity, it turns out Whitmore College has its own dark secrets. But don’t worry, TVD fans, freshman year will bond Elena and Caroline “in a really good way.” However, things may start to derail for the BFFs when they meet Professor Buzzkill... 

Enter Dr. Wes Maxfield. Elena and Caroline's professor is described as "a brilliant biology professor" at Whitmore College who “makes fast enemies” with the two freshmen. But he's not just another pretty face with a cocky attitude. Elena and Caroline start to suspect their bio teacher of “hiding a dark and dangerous secret.” Looks like these girls couldn't escape trouble for long!

Damon is still in Mystic Falls. Yes, this means after four seasons of will they/won’t they sexual tension, newly united Damon and Elena will once again be separated by distance. But at least they had an entire summer together — which no doubt included some sexy times in the Salvatore mansion — before Elena left for Whitmore.

Matt and Rebekah are in Prague — having a threesome?! Oh, Matt Donovan, look how much you’ve changed! In the Season 5 premiere, Mabekah are still having the time of their lives in Europe, and it looks like Matt is really breaking out of his comfort zone.

Showrunner Julie Plec recently told MTV’s Hollywood Crush that the couple will be joined by a “mysterious” Russian beauty named Nadia for a bedroom tryst! Julie said we’ll get to see the hot hookup in flashback in the premiere, adding, “... we get to see a nice little moment, in quotes — define it as you like — where Rebekah and Matt are living life to its fullest in Prague."

Rebekah heads to New Orleans. Rebekah is expected to show up in The Vampire Diaries Season 5, Episode 1, then move on to The Originals for its second episode. So what brings Rebekah to N’awlins? Elijah. Ultimately, Rebekah’s love for her older brother brings her (and her signature sass) to Louisiana for some quality family time.

Silas takes over. At this year’s Comic-Con panel, fans were treated to an intense premiere clip of Silas addressing what seemed to be a compelled group of humans at the Mystic Falls End of Summer Party.

“This summer I have consumed an immeasurable amount of blood and I have found myself getting stronger and stronger every day,” Silas says to the captivated Mystic Falls crowd. “And I started to wonder, what are the limits to my powers? How many people can I influence? Two? Ten? An entire town square?”

Stefan is having hallucinations. We know Damon will figure out something is up with his brother early on in the season, but until they can get to Stefan at the bottom of the quarry, the sensitive Salvatore will have to endure even more mental and physical torture as he drowns, dies, and comes to life in a seemingly never-ending vicious cycle. Oh, and he’s also been suffering from painful hallucinations. Something tells us he's seeing visions of Elena. 

Kissing, kissing, and more kissing. TVD scribe Caroline Dries tweeted the following teases about the upcoming premiere: "kissing. kissing. kissing. murder. kissing. kissing. kissing. death." We're going to assume Elena and Damon are the ones doing all the kissing — and there's a potentially steamy moment between Silas and Katherine — but who's dying?! 

Death. The Season 5 premiere will feature not one, but two deaths. One death will hit one of the core characters hard (we're already sobbing), while the other will spark one of the season's central mysteries. The Vampire Diaries is getting back to its murder mystery roots, and we couldn't be more excited! 

Are you excited for the Season 5 premiere, TVD fans? Sound off in the comments to let us know what you’re most excited for.

Catch the Season 5 premiere of The Vampire Diaries on Thursday, October 3, 2013, at 8 p.m. ET on The CW.

Crystal Bell is an editor at Wetpaint Entertainment and our resident fangirl for all things The Vampire Diaries. Follow her on Twitter and Google+!